ナビゲーション
現在位置: ホーム / イベント / その他のイベント / 理化学研究所-日本薬剤学会英語セミナー共催シンポジウム:    2015/6/16

理化学研究所-日本薬剤学会英語セミナー共催シンポジウム:    2015/6/16

イベント詳細

日時

2015年06月16日
12時30分 から 17時45分 まで

カレンダーに追加

Open symposium in Sugiyama’s Laboratory
“Recent Development and Perspective of DMPK Research”

Co-organized by APSTJ Global Education Seminar

Time and Venue

Date: June 16 (Tue): 12:30-17:45
Venue:  Riken Yokohama Koryu-toh

Program

12:30-13:10 (30+10)  Ronald S Obach  (Pfizer)
Recent Challenges in Predicting Drug Metabolism and How We Are Trying to Solve Them

13:10-13:50 (30+10)  Amit Kalgutkar (Pfizer)
Toxicophores in Drug Design: Potential for "Trouble"?

13:50-14:30 (30+10)  Peter Bonate (Astellas)
“Compound selection based on PK/PD modeling in oncology”

14:30-15:10 (30+10)  Yuichi Sugiyama (RIKEN)
Prediction of complex DDI from in vitro data on metabolism and transport

15:10-15:30    Break

15:30-15:50 (15+5)   Sumito Ito and Satoshi Senda (Genomembrane)
Joint Project with RIKEN Sugiyama’s Lab:
Establishment of the transporter expression system for drug-induced tissue(hepatic and renal) injury prediction

15:50-16:15 (15+10)  Yoshihisa Shitara (Meiji Seika Pharma)
Kinetic analysis of time dependent inhibition of cyclosporin A for OATP1B1 mediated hepatic uptake of substrates

16:15-16:40 (15+10)   Saki Izumi and Yoshitane Nozaki (Eisai)
Impact of substrate selection on in vitro OATP1B1 inhibition profiles for the prediction of DDIs

16:40-17:05 (15+10)   Tomohisa Nakada (Mitsubishi Tanabe Pharma)
Estimation of unbound intracellular–medium(plasma) concentration ratios (Kpuu) of Poorly-Metabolised Anionic Drugs Using Rat and Human Hepatocytes

17:05- 17:30 (15+10)   Ryuta Asaumi (Ono Pharma)
Establishment of rifampicin PBPK modeling which predicts all kinds of interactions including induction / inhibition of enzymes and transporters.

17:30-17:45  Concluding remarks
Ronald S Obach,  Yuichi Sugiyama,

参加申込方法

下記事項を添えてメールにてお申込み下さい。
(1)参加者ご氏名
(2)ご所属
(3)Email
(4)電話番号

申込先メールアドレス: info@riken-sugiyama.jp
参加申込締切: 6月9日(火)12時まで