Archives: 2004-2007

East-West Joint 2007

September 14, 2007 (10:30-18:30)
at Lecture Hall (Pharmaceutical Science Research Building, 2F), Grad. Sch. of Pharmaceutical Sciences, the Univ. of Tokyo

10:30-10:40
Mariko Morishita
Hoshi Univ.

10:40-11:40 (Chairperson: S. Yamashita, Setsunan Univ.)
Keith Hutchison
Vice President R&D, CAPSUGEL Div. of Pfizer Inc.
Case studies on development of liquid-filled capsule formulations

11:40-12:20 (Chairperson: K. Maeda, the Univ. of Tokyo)
Yukio Kato
Grad. Sch. of Natural Science and Technology, Kanazawa Univ.
Role of SLC transporters and their adaptor proteins in intestinal drug absorption

13:30-14:10 (Chairperson: T. Ishida, the Univ. of Tokushima)
Takashi Okura
Sch. of Pharmaceutical Sciences, Teikyo Univ.
Blood-brain barrier transport of cationic drugs

14:10-14:50 (Chairperson: T. Ozeki, Tokyo Univ. of Pharmacy and Life Sciences)
Ken-ichi Ogawara
Grad. Sch. of Medicine, Dentistry and Pharmaceutical Sciences, Okayama Univ.
Determinants to be taken into considerations for optimization of nanoparticulate drug carriers

14:50-15:30 (Chairperson: M. Nishikawa, Kyoto Univ.)
Yoshinori Onuki
Hoshi Univ.
Formulation optimization of photocross linked polyacrylic acid hydrogel as an adhesive for dermatological patches Break

15:40-16:40 (Chairperson: K. Moribe, Chiba Univ.)
Hans Lenneras
Uppsala Univ.
Gastrointestinal drug absorption: experiences from in vivo dissolution and permeability studies in humans

16:40-16:50
Shinji Sakuma
Setsunan Univ.

17:00-18:30 at Sanjo Kaikan

West 2007-2

July 24, 2007 (14:00~9:00)
at EducationBuilding/Main Building, Grad. Sch. of Pharmaceutical Sciences, Kyoto Univ.

at Multimedia room (Education Building)

14:00-14:40 (Chairperson: S. Sakuma, Setsunan Univ.)
Kentaro Kogure
Dept. of Pharmaceutical Sciences, Kyoto Pharmaceutical Univ.
Octaarginine-modified multifunctional envelope-type nanoparticles for gene delivery
 
14:40-15:20 (Chairperson: S. Kishimoto, Kobe Gakuin Univ.)
Yuki Takahashi
Dept. of Pharmaceutical Sciences, Kyoto Univ.
Development of in vivo RNA interference-based cancer therapies
 
15:20-16:00 (Chairperson: T. Takagi, Dainippon Sumitomo Pharma Co., Ltd.)
Fumie K. Tanno
Specialty Chemicals Research Center, Shin-Etsu Chemical Co., Ltd.
Hypromellose acetate succinate (HPMCAS) as a carrier in solid dispersions

at Lecture Hall (Main Building)

16:20-17:30 (Chairperson: Y. Takakura, Kyoto Univ.)
Dexi Liu
Professor, Sch. of Pharmacy, Univ. of Pittsburgh
Gene Transfer by Naked DNA

17:30-19:00  at Reception Hall (Education Building, 1F)

East 2007-1

July 17, 2007 (14:30〜18:40)
at Memorial Hall 2F, Grad. Sch. of Pharmaceutical Sciences, Chiba Univ.

14:30-15:30 (Chairperson: K. Moribe, Chiba Univ.)
Hyo-Kyung Han
Col. of Pharmacy, Chosun Univ.
Implication of drug transporters in the new drug discovery and development

15:40-16:20 (Chairperson:Y. Shitara, Chiba Univ.)
Tsuneo Deguchi
DMPK Research Laboratories, Daiichi Sankyo Co., Ltd.
Pharmacokinetic study of anionic uremic toxins
 
16:20-17:00 (Chairperson: K. Nakamura, Terumo Corporation)
Tomohiro Endo
Faculty of Pharmaceutical Sciences, Hoshi Univ.
Physicochemical properties of large-ring cyclodextrins

17:10-18:40 at Restaurant　COLZA (Keyaki Kaikan 1F)

West 2007-1

June 19, 2007 (13:15-15:45)
at Campus Plaza Kyoto, 2F, Meeting Room 2 (http://www.consortium.or.jp/campusplaza/access.html)

13:15-13:55 (Chairperson: S. Sakuma, Setsunan Univ.)
Hiromitsu Yamamoto
Sch. of Pharmacy, Aichi Gakuin Univ.
Surface modification of biodegradable polymeric nanoparticle for drug delivery system
 
13:55-14:35(Chairperson: K. Iwanaga, Osaka Univ. of Pharm. Sci.)
Hidetoshi Myojo
Pharmaceutical Development Dept., CMC Development Laboratories, Shionogi & Co., Ltd.
Investigation of ethylcellulose coated fine drug-layered pellets using a confocal laser scanning microscope (CLSM)
Break 10 min

14:45-15:45 (Chairperson: S. Yamashita, Setsunan Univ.)
Peter Langguth
Professor, Sch. of Pharmacy, Johannes Gutenberg Univ.
Evolution of oral drug delivery systems

West 2006-3

November 28, 2006 (14:00〜19:00)
at Campus Plaza Kyoto, 4F, Lecture Room 4 (http://www.consortium.or.jp/campusplaza/access.html)

14:00-14:40 (Chairperson: S. Sakuma, Setsunan Univ.)
Toshiyuki Kida
Dept. of Applied Chemistry, Grad. Sch. of Engineering, Osaka Univ.
Controlled release of entrapped substances from it-PMMA/st-PMMA stereocomplex hollow capsules
 
14:40-15:20 (Chairperson: K. Yano, Ono Pharmaceutical Co., Ltd.)
Hiroshi Mizuuchi
Exploratory DMPK, Exploratory Toxicology & DMPK Research Laboratory, Tanabe Seiyaku Co., Ltd.
Room temperature ionic liquids as pharmaceutical solvents
 
15:20-16:00 (Chairperson: M. Nishikawa, Kyoto Univ.)
Barichello Jose Mario
Dept. of Pharmacokinetics & Biopharmaceutics, Grad. Sch. of Pharmaceutical Sciences, The Univ. of Tokushima
Physicochemical characteristics of an improved liposomal siRNA delivery system

16:10-17:20 (Chairperson: Y. Takakura, Kyoto Univ.)
Jindrich Kopecek
Professor, Sch. of Pharmacy, Univ. of Utah
Polymeric nanomedicines for cancer therapy: From concept to clinic

17:30-19:00  at Restaurant Shiki (APA Hotel, Kyoto-Ekimae, 1F)

本セミナーは京都大学大学院薬学研究科生物薬剤学セミナーとの共催です。

East 2006-3

September 29, 2006 (13:30-18:30)
at Memorial Hall 2F, Grad. Sch. of Pharmaceutical Sciences, Chiba Univ.

今回のPlenary Lectureには、CAPSUGELのJan Vertommen先生をお招きして、”Development and preparation of liquid based formulations in hard gelatin capsules”という演題でご講演をしていただくことになりました。その他の演者は、森部久仁一(千葉大学)、保地毅彦先生(アステラス製薬)、上田秀雄先生(城西大学)で、製剤化およびDDSに関する研究に従事している研究者です。「英語を聞き話す機会を持つ」という趣旨のセミナーですので、どうぞ専門分野に限らず、お気軽に御参加くださいますよう、何卒宜しくお願いいたします。

13:30-14:30 (Chairperson: K. Moribe, Chiba Univ.)
Jan Vertommen
Director, Development Centre Pharma, CAPSUGEL Div. of Pfizer Inc.
Development and preparation of liquid based formulations in hard gelatin capsules

14:30-15:10 (Chairperson: K. Nakamura, Terumo Co.)
Kunikazu Moribe
Grad. Sch. of Pharmaceutical Sciences, Chiba Univ.
Solubilization and nanoparticle formation of drug substances occurred by the co-grinding with excipients

15:20-16:00 (Chairperson: T. Ozeki, Tokyo Univ. of Pharmacy and Life Science)
Takehiko Yasuji
Pharmaceutical Research and Technology Labs., Astellas Pharma Inc.
Particle design of poorly water-soluble drug substances using supercritical fluid technologies
 
16:00-16:40 (Chairperson: K. Maeda, Univ. of Tokyo)
Hideo Ueda
Faculty of Pharmaceutical Sciences, Josai Univ.
In vitro and in vivo characterization of low frequency sonophoresis on transdermal delivery of macromolecules

17:00-18:30 at Restaurant COLZA (Keyaki Kaikan 1F)

East 2006-2

July 18, 2006 (13:30~8:30)
at Reception Hall (Keyaki Kaikan, 3F), Grad. Sch. of Pharmaceutical Sciences, Chiba Univ.

13:30-14:30 (Chairperson: K. Moribe, Chiba Univ.)
Adam Watkinson
Professor, Chief Scientific Officer, ACRUX Ltd.
Metered Dose Transdermal Sprays - a new direction for transdermal drug delivery?

14:30-15:10 (Chairperson: T. Ozeki, Tokyo Univ. of Pharmacy and Life Science)
Hiroaki Todo
Faculty of Pharmaceutical Sciences, Josai Univ.
Movement of injection-like drug delivery from enhanced transdermal drug delivery

15:20-16:00 (Chairperson: E. Shitara, Chiba Univ.)
Toyofumi Suzuki
Dept. of Pharmaceutics, Col. of Pharmacy, Nihon Univ.
Imaging endogenous gene expression in brain cancer in vivo with 111In-peptide nucleic acid antisense radiopharmaceuticals and brain drug-targeting technology
 
16:00-16:40 (Chairperson: K. Nakamura, Terumo Co.)
Yoichi Negishi
Sch. of Pharmacy, Tokyo Univ. of Pharmacy and Life Science
Gene delivery using ultrasound contrast agents

17:00-18:30 at Restaurant COLZA (Keyaki Kaikan 1F)

West 2006-1

May 22, 2006 (14:30~9:00)
at Education Building/Main Building, Grad. Sch. of Pharmaceutical Sciences, Kyoto Univ.

at Multimedia room (Education Building, 1F)

14:30-15:15 (Chairperson: M. Nishikawa, Kyoto Univ.)
Shinji Sakuma
Dept. of Pharmaceutical Sciences, Setsunan Univ.
Lectin-immobilized fluorescent nanocarrier with surface poly(N-vinylacetamide) chains as an endoscopic imaging agent for earlier colorectal cancer
 
15:15-16:00(Chairperson: T. Fujita, Kyoto Pharmaceutical Univ.)
Yoshimasa Kobayashi
Drug Metabolism & Physicochemistry Res. Lab., R & D Div., Daiichi Pharm. Co., Ltd.
“CALTA”, A novel structure-physicochemical property-activity profiling method: Application to the in silico prediction research for CYP3A4 inhibition

at Lecture Hall (Main Building, 16:30-17:40)

16:30-17:40 (Chairperson: Y. Takakura, Kyoto Univ.)
Gordon Amidon
Professor, Col. of Pharmacy, Univ. of Michigan
BCS class I permeability determination and FDA biowaivers

17:40- at Reception Hall (New Research Building, 1F)

本セミナーは京都大学大学院薬学研究科生物薬剤学セミナーとの共催です。
G. Amidon先生のご講演及び懇親会は一般参加を受け付けております。

East 2006-1

April 10, 2006 (13:30 -19:00)
at Lecture Hall (Pharmaceutical Science Research Building, 2F), Grad. Sch. of Pharmaceutical Sciences, the Univ. of Tokyo

13:30-14:30 (Chairperson: K. Moribe, Chiba Univ.)
Kenneth Thummel
Professor of Pharmaceutics, Associate Dean for Research & New Initiatives, Univ. of Washington Sch. of Pharmacy
Inter-relationship between 1,25-dihydroxyvitamin D3 disposition and CYP3A4 and CYP24 expression

14:40-15:20 (Chairperson: N. Masubuchi, Daiichi Pharmaceutical Co., Ltd.)
Kaoru Kobayashi
Dept. of Pharmacology and Toxicology, Grad.Sch. of Pharmaceutical Sciences, Chiba Univ.
Involvement of hepatocyte nuclear factor 4 alpha in the different expression level between CYP2C9 and CYP2C19 in the human liver
 
15:20-16:00 (Chairperson: K. Nakamura, Terumo Co.)
Ryo Suzuki
Dept. of Biopharmaceutics, Sch. of Pharmaceutical Sciences, Teikyo Univ.
Cancer immunotherapy with IgG-modified liposomes as an antigen delivery carrier

16:10-16:50 (Chairperson: T. Deguchi, Sankyo Co., Ltd.)
Kousei Ito
Dept. of Pharmacy, the Univ. of Tokyo Hospital
Regulation of biliary transporter surface expression

17:30-19:00 at Conference room #1, Sanjo Kaikan

East 2005-3/27th Mini-Symposium of Dept. of Molecular Pharmacokinetics, the Univ. of Tokyo

"Emerging trends in improvement of oral and pulmonary drug absorption"

September 28, 2005 (13:00-18:00)
at Lecture Hall (Pharmaceutical Science Research Building, 2F), Grad. Sch. of Pharmaceutical Sciences, the Univ. of Tokyo

13:00-13:10

13:10-13:20
Daumesnil Roland
CAPSUGEL Japan Inc.
How to fully exploit the market potential of poorly soluble actives? Case studies

13:20-14:00
Hassan Benameur
CAPSUGEL Japan Inc.
CAPSUGEL rational approach on self emulsifying and related system development

14:00-14:50
Shinji Yamashita
Setunan Univ.
Intestinal transporters and enzymes: their role as a barrier against oral drug delivery

15:10-15:40
Toshihide Takagi (Dainippon Pharmaceutical Co., Ltd.)
Biopharmaceutical Classification of the Top Oral Drug Products in the United States, Great Britain, Spain, and Japan
 
15:40-16:10
Mariko Morishita (Hoshi Univ.)
Impact of pharmaceutical excipients on intestinal transporter function
 
16:10-16:40
Motohiro Kato (Chugai Pharmaceutical Co., Ltd.)
Prediction of the first-pass intestinal metabolic clearance and intestinal enzyme mediated drug-drug interaction based on the in vitro data

17:00-17:30
Kazuhiro Sako (Astellas Pharma Inc.)
Oral controlled absorption system (OCAS); Stable colonic drug release technique for hydrophilic gel-forming matrices
 
17:30-18:00
Yoshiyuki Yabe (Sankyo Co., Ltd.)
Sustained release formulation of compound X for pulmonary drug delivery

East 2005-2

June 1, 2005 (13:30~16:50)
at Lecture Hall (Pharmaceutical Science Research Building, 2F), Grad. Sch. of Pharmaceutical Sciences, the Univ. of Tokyo

13:30-14:30 (Chairperson: M. Morishita, Hoshi Univ.)
Geoffrey T. Tucker
Academic Unit of Clinical Pharmacology, Univ. of Sheffield, United Kingdom
Predicting drug clearance and drug-drug interactions

14:40-15:20 (Chairperson: TBA)
Naomi Nagai
Office of New Drug II, Center for Product Evaluation, Pharmaceuticals and Medical Devices Agency
Drug Interaction Studies in the Recent Japanese New Drug Applications
 
15:20-16:00 (Chairperson: TBA)
Kazuho Okudaira
Dept. of Pharmacokinetics and Biopharmaceutics, Sch. of Pharmaceutical Sciences, Toho Univ.
Effect of Troleandomycin on CYP3A Activity: Inhibition or Induction?

16:10-16:50 (Chairperson: TBA)
Tetsuya Ozeki
Pharmaceutics and Drug Delivery, Sch. of Pharmacy, Tokyo Univ. of Pharmacy and Life Science
Composite microspheres containing nanoparticles of polymers and water-insoluble drugs

17:30- at the Lobby of Library

East 2005-1

January 19, 2005 (14:30-17:30)
at Lecture Hall (Pharmaceutical Science Research Building, 2F),　Grad. Sch. of Pharmaceutical Sciences, the Univ. of Tokyo

14:30-15:30 (Chairperson: M. Morishita, Hoshi Univ.)
Hugues Dolgos
DMPK Development Dept.
Institute of Drug Metabolism and Pharmacokinetics, Merck KGaA, Germany
What are the differences in the Development of NCE´s and NBE´s?

15:30-16:10 (Chairperson: N. Utoguchi, Teikyo Univ.)
Yuji Kasuya
DDS Research Group, Pharmaceutical Development Laboratories, Sankyo Co., Ltd.
HPMA Copolymer? Geldanamycin Derivative Conjugates: Design, Synthesis, Characterization and Biological Evaluations

16:20-17:00 (Chairperson: Y. Shitara, Showa Univ.)
Noriko Okudaira
Drug Metabolism & Physicochemistry Research Laboratory, Daiichi Pharmaceutical Co., LTD.
Technical Difficulties in Predicting in vivo Inhibition of CYP Isozymes from in vitro Data

17:30- at Sanjo Kaikan

East 2004-2

July 17, 2004 (13:30~16:40)
at the Otani Hall, Hoshi Univ.

13:30-14:30 (Chairperson: M. Morishita, Hoshi Univ.)
Nicholas A. Peppas
Biomaterials, Drug Delivery and Molecular Recognition Laboratories, Dept.s of Chemical Engineering, Biomedical Engineering and Pharmaceutics, The Univ. of Texas at Austin
Cellular and Molecular Evaluation of Oral Delivery Systems for Chemotherapeutic Agents

14:30-15:10 (Chairperson: Y. Yabe, Sankyo Co. Ltd.)
Koji Nakamura
Dept. of Pharmaceutics, Hoshi Univ.
Effect of P (MAA-g-EG) hydrogels on Insulin Absorption through Small Intestinal Mucosa

15:20-16:00 (Chairperson: Y. Shitara, Showa Univ.)
Kunikazu Moribe
Grad. Sch. of Pharmaceutical Sciences, Chiba Univ.
Preparation of drug nanoparticles by grinding
 
16:00-16:40 (Chairperson: E. Yonemochi, Toho Univ.)
Toshiro Fukami
Col. of Pharmacy, Nihon Univ.
Enhancement of water solubility of fullerene by cogrinding with cycloamylose, novel cyclic α-1, 4-glucans

17:00- at Stella

East 2004-1

May 19, 2004 (15:30 -18:00)
at the Memorial Auditorium, the Univ. of Tokyo

15:30-16:30 (Chairperson: M. Morishita, Hoshi Univ.)
Tadanobu Inaba
Professor & Grad. Coordinator, Dept. of Pharmacology, Univ. of Toronto
Inhibitory effects of human and bovine serum albumins on CYP enzymes: Free drug hypothesis test ratio

16:40-17:20 (Chairperson: K. Moribe, Chiba Univ.)
Noriko Masubuchi
Daiichi Pharmaceutical Co., Ltd.
Preclinical development of macromolecular carrier conjugated anti-cancer drug

17:20-18:00 (Chairperson: K. Ito, Hoshi Univ.)
Kazuya Maeda
Dept. of Molecular Pharmacokinetics, Grad.Sch. of Pharmaceutical Sciences, the Univ. of Tokyo
Importance of organic anion transporting polypeptide 2 (OATP2) in the human hepatic uptake of xenobiotics ~its contribution and impact of genetic polymorphism~

18:30-20:00 at Sanjo Kaikan